Publikationen

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Ecological significance of sea-dumped chemical munitions: acute aquatic toxicity of arsenic-based chemical warfare agents (Czub M, Nawała J, …, Maser E, … Limnol Oceanogr – in revision)

Ocean Pollution. In: SDG 14 - Transitioning to Sustainable Life below Water. (MDPI Books - under review)

Exposure to dissolved TNT causes multilevel biological effects in Baltic mussels (Mytilus spp.) (Mar Environ Res - under review)

Marine bivalves as bioindicators for environmental pollutants with focus on dumped munitions in the sea: A review
Strehse, J.S. and Maser, E, (2020) Mar Environ Res. doi: 10.1016/j.marenvres.2020.105006

“Don’t Blast” - Blast-in-place (BiP) operations of dumped World War munitions in the oceans significantly increase hazards to the environment and the human seafood consumer
Maser, E. and Strehse, J. S., (2020), Arch. Toxicol. doi: 10.1007/s00204-020-02743-0

Explosive Ordnance in the Baltic Sea: New Tools for Decision Makers
Frey, T., Beldowski, J. and Maser, E. (2020), The Journal of Conventional Weapons Destruction: Vol. 23 : Iss. 3 , Article 11.

Sex-specificity in lung cancer risk.
Stapelfeld, C., Dammann, C. and Maser, E. (2020), Int. J. Cancer, 146: 2376-2382. doi: 10.1002/ijc.32716">10.1002/ijc.32716

 

 

Practical Guide for Environmental Monitoring of Conventional Munitions in the Seas.
Greinert J, Appel D, Beck AJ, Eggert A, Gräwe U, Kampmeier M, Martin H-J,Maser E, Schlosser C,Song Y,Strehse JS, van der Lee E, Vortmeyer-Kley R, Wichert U, Frey T (2019) doi:10.3289/GEOMAR_REP_NS_54_2019

Carbonyl reductase sniffer from the model organism daphnia: Cloning, substrate determination and inhibitory sensitivity.
Strehse JS, Protopapas N and Maser E. JChem Biol Interact. 2019 Jul 1;307:29-36. doi: 10.1016/j.cbi.2019.04.011. Epub 2019 Apr 13.

Potent inhibition of human carbonyl reductase 1 (CBR1) by the prenylated chalconoid xanthohumol and its related prenylflavonoids isoxanthohumol and 8-prenylnaringenin.
Seliger JM, Martin HJ and Maser E., Hintzpeter J. J Chem Biol Interact. 2019 May 25;305:156-162. doi: 10.1016/j.cbi.2019.02.031. Epub 2019 Mar 6.

Expression and activity of the cortisol-activating enzyme 11β-hydroxysteroid dehydrogenase type 1 is tissue and species-specific.
Dammann C, Stapelfeld C and Maser E. J Chem Biol Interact. 2019 Apr 25;303:57-61. doi: 10.1016/j.cbi.2019.02.018. Epub 2019 Feb 21. Review.

A novel dehydrogenase 17β-HSDx from Rhodococcus sp. P14 with potential application in bioremediation of steroids contaminated environment.
Ye X, Peng T, Feng J, Yang Q, Pratush A, Xiong G, Huang T and Hu Z. J Hazard Mater. 2019 Jan 15;362:170-177. doi: 10.1016/j.jhazmat.2018.09.023. Epub 2018 Sep 10.

Isolation and characterization of a marine testosterone-degrading bacterium: Vibrio sp. N3.
Peng T, Chen QK, Lun JS, Pratush A, Xiong GM, Huang TW and Hu Z.Rev Argent Microbiol. 2018 Oct 5. pii: S0325-7541(18)30082-8. doi: 10.1016/j.ram.2018.05.005.

Monitoring von Giftstoffen im Meer
Strehse J S, Baas J and Maser E, BioSpektrum 25(1):26-28 • February 2019 DOI: 10.1007/s12268-019-0998-x

 

 

Crystal structure and catalytic characterization of the dehydrogenase/reductase SDR family member 4 (DHRS4) from Caenorhabditis elegans.
Kisiela M, Faust A, Ebert B, Maser E, Scheidig AJ.FEBS J. 2018 Jan; 285(2):275-293. doi: 10.1111/febs.14337. Epub 2017 Nov 28. PubMed PMID: 29151266. Epub 2017 Nov 28.

The hop-derived compounds xanthohumol, isoxanthohumol and 8-prenylnaringenin are tight-binding inhibitors of human aldo-keto reductases 1B1 and 1B10.
Seliger JM, Misuri L, Maser E, Hintzpeter J. J Enzyme Inhib Med Chem. 2018 Dec;33(1):607-614. doi: 10.1080/14756366.2018.1437728. PubMed PMID: 29532688; PubMed Central PMCID: PMC6010053.13. March 2018

Selective Inhibition of Human AKR1B10 by n-Humulone, Adhumulone and Cohumulone Isolated from Humulus lupulus Extract.
Seliger JM, Cicek SS, Witt LT, Martin HJ, Maser E, Hintzpeter J.Molecules 2018, 23(11), 3041; doi: https://doi.org/10.3390/molecules23113041. PubMed PMID: 30469331; PubMed Central PMCID: PMC6278539. 21. November 2018

Carbonyl reductases from Daphnia are regulated by redox cycling compounds.
Ebert B, Ebert D, Koebsch K, Maser E, Kisiela M. FEBS J. 2018 Aug;285(15):2869-2887. doi: 10.1111/febs.14578. Epub 2018 Jun 20.

Bioaccumulation of 2,4,6-trinitrotoluene (TNT) and its metabolites leaking from corroded munition in transplanted blue mussels (M. edulis).
Appel D, Strehse JS, Martin HJ, Maser E. Mar Pollut Bull. 2018 Oct;135:1072-1078. doi: 10.1016/j.marpolbul.2018.08.028. Epub 2018 Aug 24. PubMed PMID: 30301003.

Munition im Meer- auf dem Weg zu einer guten Lösung?
C. Böttcher, J. Sternheim, J. Strehse. August 2018, Wasser und Abfall Heft 7-8, Springer Verlag, Seite 36-40 (5 Seiten).

A novel dehydrogenase 17β-HSDx from Rhodococcus sp. P14 with potential application in bioremediation of steroids contaminated environment.
Ye X, Peng T, Feng J, Yang Q, Pratush A, Xiong G, Huang T, Hu Z. J Hazard Mater. 2019 Jan 15;362:170-177. doi: 10.1016/j.jhazmat.2018.09.023. Epub 2018 Sep 10.

Isolation and characterization of a marine testosterone-degrading bacterium: Vibrio sp. N3.
Peng T, Chen QK, Lun JS, Pratush A, Xiong GM, Huang TW, Hu Z. Rev Argent Microbiol. 2018 Oct 5. pii: S0325-7541(18)30082-8. doi: 10.1016/j.ram.2018.05.005.

Degradation of Oestrogen and an Oestrogen-like Compound in Chicken Faeces by Bacteria.
Miao Xu & Shining Han & Ningning Lu & Xin Zhang & Junmei Liu & Dong Liu & Guangming Xiong & Liquan Guo. Water Air Soil Pollut (2018) 229:337

 

 

A novel 17β-hydroxysteroid dehydrogenase in Rhodococcus sp. P14 for transforming 17β-estradiol to estrone.
Xueying Ye, Hui Wang, Jie Kan, Jin Li, Tongwang Huang, Guangming Xiong, Zhong Hu CHEMICO-BIOLOGICAL INTERACTIONS / 276 / 105−112

Functional analysis of a novel repressor LuxR in Comamonas testosteroni.
Ye Ji, Tianyuan Pan, Yang Zhang, Guangming Xiong, Yuanhua Yu, CHEMICO-BIOLOGICAL INTERACTIONS / 276 / 113−120

Quantitative determination of testosterone levels with biolayer interferometry.
Zhang H, Li W, Luo H, Xiong G, Yu Y, CHEMICO-BIOLOGICAL INTERACTIONS / 276 / 141−148

Chrysin and silibinin sensitize human glioblastoma cells for arsenic trioxide.
Gülden M, Appel D, Syska M, Uecker S, Wages F, Seibert H, FOOD AND CHEMICAL TOXICOLOGY / 105 / 486-497

Sex hormones reduce NNK detoxification through inhibition of short-chain dehydrogenases/reductases and aldo-keto reductases in vitro.
Stapelfeld C, Maser E. Chem Biol Interact. 2017 Oct 1;276:167-173. doi: 10.1016/j.cbi.2017.02.016.

Body Burden of Dichlorodiphenyl Dichloroethene (DDE) and Childhood Pulmonary Function.
Balte P P, Kühr J, Kruse H, Karmaus W J J. Int J Environ Res Public Health. 2017 Nov 14;14(11). pii: E1376. doi: 10.3390/ijerph14111376.

Regulation of 11β-hydroxysteroid dehydrogenase type 1 following caloric restriction and re-feeding is species dependent.
Loerz C, Staab-Weijnitz C, Huebbe P, Giller K, Metges C, Rimbach G, Maser E. Drug Metab Rev. 2016 May;48(2):183-217. doi: 10.3109/03602532.2016.1167902.

Different inhibitory potential of sex hormones on NNK detoxification in vitro: A possible explanation for gender-specific lung cancer risk.
Stapelfeld C, Neumann KT, Maser E. Cancer Lett. 2017 Oct 1;405:120-126. doi: 10.1016/j.canlet.2017.07.016.

The cortisol-activating enzyme 11β-hydroxysteroid dehydrogenase type 1 in skeletal muscle in the pathogenesis of the metabolic syndrome.
Loerz C, Maser E. J Steroid Biochem Mol Biol. 2017 Nov;174:65-71. doi: 10.1016/j.jsbmb.2017.07.030.

Biomonitoring of 2,4,6-trinitrotoluene and degradation products in the marine environment with transplanted blue mussels (M. edulis).
Strehse JS, Appel D, Geist C, Martin HJ, Maser E. Toxicology. 2017 Sep 1;390:117-123. doi: 10.1016/j.tox.2017.09.004.

Crystal structure and catalytic characterization of the dehydrogenase/reductase SDR family member 4 (DHRS4) from Caenorhabditis elegans.
Kisiela M, Faust A, Ebert B, Maser E, Scheidig AJ. FEBS J. 2017 Nov 19. doi: 10.1111/febs.14337.

 

Transcriptional regulation of human and murine short-chain dehydrogenase/reductases (SDRs) - an in silico approach.
Ebert B, Kisiela M, Maser E. Drug Metab Rev. 2016 May;48(2):183-217. doi: 10.3109/03602532.2016.1167902.

Suspended micro-sized PVC particles impair the performance and decrease survival in the Asian green mussel Perna viridis.
Rist SE, Assidqi K, Zamani NP, Appel D, Perschke M, Huhn M, Lenz M. Mar Pollut Bull. 2016 Oct 15;111(1-2):213-20. doi: 10.1016/j.marpolbul.2016.07.006.

Inhibition of human anthracycline reductases by emodin - A possible remedy for anthracycline resistance.
Hintzpeter J, Seliger JM, Hofman J, Martin HJ, Wsol V, Maser E. Toxicol Appl Pharmacol. 2016 Feb 15;293:21-9. doi: 10.1016/j.taap.2016.01.003. Epub 2016 Jan 7. PMID: 26773812.

Regulation of alkane degradation pathway by a TetR family repressor via an autoregulation positive feedback mechanism in a Gram-positive Dietzia bacterium.
Liang JL, Nie Y, Wang M, Xiong G, Wang YP, Maser E, Wu XL. Mol Microbiol. 2016 Jan;99(2):338-59. doi: 10.1111/mmi.13232. Epub 2015 Oct 27. PMID:26418273.

 

 

Incipient cytotoxicity: A time-independent measure of cytotoxic potency in vitro.
Gülden M, Kähler D, Seibert H. Toxicology. 2015 Sep 1;335:35-45. doi: 10.1016/j.tox.2015.07.002. Epub 2015 Jul 6. PMID: 26159257.

Ingested microplastics (>100 μm) are translocated to organs of the tropical fiddler crab Uca rapax.
Brennecke D, Ferreira EC, Costa TM, Appel D, da Gama BA, Lenz M. Mar Pollut Bull. 2015 Jul 15;96(1-2):491-5. doi: 10.1016/j.marpolbul.2015.05.001. Epub 2015 May 23. PMID: 26013589.

Isolation and identification of a repressor TetR for 3,17β-HSD expressional regulation in Comamonas testosteroni.
Pan T, Huang P, Xiong G, Maser E. Chem Biol Interact. 2015 Jun 5;234:205-12. doi: 10.1016/j.cbi.2014.12.034. Epub 2015 Jan 2. PMID: 25559855.

Curcumin is a tight-binding inhibitor of the most efficient human daunorubicin reductase--Carbonyl reductase 1.
Hintzpeter J, Hornung J, Ebert B, Martin HJ, Maser E. Chem Biol Interact. 2015 Jun 5;234:162-8. doi: 10.1016/j.cbi.2014.12.019. Epub 2014 Dec 22. PMID: 25541467.

Construction of a biosensor mutant of Comamonas testosteroni for testosterone determination by cloning the EGFP gene downstream to the regulatory region of the 3,17β-HSD gene.
Xiong G, Maser E. Chem Biol Interact. 2015 Jun 5;234:188-96. doi: 10.1016/j.cbi.2014.11.014. Epub 2014 Dec 3. PMID: 25481546.

Identification and isolation of a regulator protein for 3,17β-HSD expressional regulation in Comamonas testosteroni.
Wu Y, Huang P, Xiong G, Maser E. Chem Biol Interact. 2015 Jun 5;234:197-204. doi: 10.1016/j.cbi.2014.11.004. Epub 2014 Nov 17. PMID: 25446854.

Reduction of lipid peroxidation products and advanced glycation end-product precursors by cyanobacterial aldo-keto reductase AKR3G1-a founding member of the AKR3G subfamily.
Hintzpeter J, Martin HJ, Maser E. FASEB J. 2015 Jan;29(1):263-73. doi: 10.1096/fj.14-258327. Epub 2014 Nov 5. PMID: 25376835.

Human DCXR - another 'moonlighting protein' involved in sugar metabolism, carbonyl detoxification, cell adhesion and male fertility?
Ebert B, Kisiela M and Maser E. Biol Biol Rev Camb Philos Soc.2015 Feb; 90(1):254-78. doi:10.1111/brv.12108. Epub 2014 Apr 10. PIMD:24720935.

In vitro toxicity testing with microplate cell cultures: Impact of cell binding.
Gülden M, Schreiner J, Seibert H. Toxicology. 2015 Jun 5;332:41-51. doi: 10.1016/j.tox.2013.11.006. Epub 2013 Nov 26. PMID: 24291469.

 

 

Green tea and one of its constituents, Epigallocatechine-3-gallate, are potent inhibitors of human 11β-hydroxysteroid dehydrogenase type 1.
Hintzpeter J, Stapelfeld C, Loerz C, Martin HJ, Maser E. PLoS One. 2014 Jan 3;9(1):e84468. doi: 10.1371/journal.pone.0084468.

Toxicity of functional nano-micro zinc oxide tetrapods: impact of cell culture conditions, cellular age and material properties.
Papavlassopoulos H, Mishra YK, Kaps S, Paulowicz I, Abdelaziz R, Elbahri M, Maser E, Adelung R, Röhl C. PLoS One. 2014 Jan 13;9(1):e84983. doi: 10.1371/journal.pone.0084983. eCollection 2014. PMID: 24454775.

Additivity, antagonism, and synergy in arsenic trioxide-induced growth inhibition of C6 glioma cells: Effects of genistein, quercetin and buthionine-sulfoximine.
Klauser E, Gülden M, Maser E, Seibert S, Seibert H. Food Chem Toxicol. 2014 Mar 12;67C:212-221. doi: 10.1016/j.fct.2014.02.039. PMID: 24632069.

 

 

Chemico-Biological Interactions. Enzymology and molecular biology of carbonyl metabolism 16. Introduction.
Plapp BV, Kedishvili NY, Rižner TL, Maser E, O'Brien PJ. Chem Biol Interact. 2013 Feb 25;202(1-3):1. doi: 10.1016/j.cbi.2013.02.004. PMID: 23497822.

S-nitrosoglutathione covalently modifies cysteine residues of human carbonyl reductase 1 and affects its activity.
Hartmanová T, Tambor V, Lenčo J, Staab-Weijnitz CA, Maser E, Wsól V. S-nitrosoglutathione covalently modifies cysteine residues of human carbonyl Reductase 1 and affects its activity. Chem Biol Interact. 2013 Feb 25;202(1-3):136- 45. doi: 10.1016/j.cbi.2012.12.011. Epub 2013 Jan 5.

In vitro toxicity testing with microplate cell cultures: Impact of cell binding.
Gülden M., Schreiner J, Seibert H. Toxicology. 2013 Nov 26. pii: S0300-483X(13)00310-7. doi: 10.1016/j.tox.2013.11.006. PMID: 24291469.

A novel transcriptional repressor PhaR for the steroid-inducible expression of the 3,17β-hydroxysteroid dehydrogenase gene in Comamonas testosteroni ATCC11996.
Li M, Xiong G, Maser E. Chem Biol Interact. 2013 Feb 25;202(1-3):116-25. doi: 10.1016/j.cbi.2012.12.014. Epub 2013 Jan 4. PMID: 23295223

Analysis and characterization of eight estradiol inducible genes and a strong promoter from the steroid degrading marine bacterial strain S19-1.
Zhang T, Xiong G, Maser E. Chem Biol Interact. 2013 Feb 25;202(1-3):159-67. doi: 10.1016/j.cbi.2012.11.018. Epub 2012 Dec 8. PMID: 23232150

Huge increase of therapeutic window at a bioactive silver/titania nanocomposite coating surface compared to solution.
Hrkac T, Röhl C, Podschun R, Zaporojtchenko V, Strunskus T, Papavlassopoulos H, Garbe-Schönberg D, Faupel F. Mater Sci Eng C Mater Biol Appl. 2013 May 1;33(4):2367-75. doi: 10.1016/j.msec.2013.01.069. Epub 2013 Feb 5. PMID: 23498271

Identification of microRNAs as a potential novel regulatory mechanism in HSD11B1 expression.
Han Y, Staab-Weijnitz CA, Xiong G, Maser E. J Steroid Biochem Mol Biol. 2013 Jan;133:129-39. doi: 10.1016/j.jsbmb.2012.09.005. Epub 2012 Sep 24. 

 

2012

 

Identification of a new steroid degrading bacterial strain H5 from the Baltic Sea and isolation of two estradiol inducible genes.
Sang Y, Xiong G, Maser E. J Steroid Biochem Mol Biol. 2012 Mar;129(1-2):22-30. doi: 10.1016/j.jsbmb.2011.01.018. Epub 2011 Feb 15 PMID: 21310233.

Identification and characterization of the LysR-type transcriptional regulator HsdR for steroid-inducible expression of the 3α-hydroxysteroid dehydrogenase/carbonyl reductase gene in Comamonas testosteroni.
Gong W, Xiong G, Maser E. Appl Environ Microbiol. 2012 Feb;78(4):941-50. doi: 10.1128/AEM.06872-11. Epub 2011 Dec 9. PMID: 22156416.

Organochlorine burdens in harbour seals from the German Wadden Sea collected during two phocine distemper epizootics and ringed seals from West Greenland waters.
Siebert U., Heidmann A., Friedhoff N., Kruse H., Rig't F., Adler S., Maser E. Journal of Environmental & Analytical Toxicology 2012, 2:126, doi: 10.4172/2161-0525.1000126.

16th Carbonyl Metabolism Meeting: from enzymology to genomics.
Maser, E. Hum Genomics. 2012 Dec 1;6:25. doi: 10.1186/1479-7364-6-25 PMID: 23199258.

THCVA-A - a new additional marker for illegal cannabis consumption.
Radünz L, Westphal F, Maser E, Rochholz G. Forensic Sci Int. 2012 Feb 10;215(1-3):171-4. doi: 10.1016/j.forsciint.2011.03.001. Epub 2011 Mar 31 PMID: 21454026.

Analysis and characterization of eight estradiol inducible genes and a strong promoter from the steroid degrading marine bacterial strain S19-1.
Zhang T, Xiong G, Maser E. Chem Biol Interact. 2013 Feb 25;202(1-3):159-67. doi: 10.1016/j.cbi.2012.11.018. Epub 2012 Dec 8. PMID: 23232150.

Identification of microRNAs as a potential novel regulatory mechanism in HSD11B1 expression.
Han Y, Staab-Weijnitz CA, Xiong G, Maser E. J Steroid Biochem Mol Biol. 2013 Jan;133:129-39. doi: 10.1016/j.jsbmb.2012.09.005. Epub 2012 Sep 24. PMID: 23017470.

Inhibition of bacterial adhesion to live human cells: Activity and cytotoxicity of synthetic mannosides.
Hartmann M, Papavlassopoulos H, Chandrasekaran V, Grabosch C, Beiroth F, Lindhorst T.K, Röhl C. FEBS Lett. 2012 May 21;586(10):1459-65. doi: 10.1016/j.febslet.2012.03.059. Epub 2012 Apr 10.

Improved method for the isolation, characterization and examination of neuromuscular and toxic properties of selected polypeptide fractions from the crude venom of the Taiwan cobra Naja naja atra.
Ständker L., Harvey AL, Fürst S, Mathes I, Forssmann WG, Escalona de Motta G, Béress L. FEBS J. 2012 Jan 17. doi: 10.1111/j.1742-4658.2012.08494.x. PMID:22251568.

Hydroxysteroid dehydrogenases (HSDs) in bacteria: a bioinformatic perspective.
Kisiela M, Skarka A, Ebert B, and Maser E. J Steroid Biochem Mol Biol. 2012 Mar;129(1-2):31-46. doi: 10.1016/j.jsbmb.2011.08.002. PMID:21884790.

Momordica charantia extract, a herbal remedy for type 2 diabetes, contains a specific 11β-hydroxysteroid dehydrogenase type 1 inhibitor.
Blum A, Loerz C, Martin HJ, Staab-Weijnitz CA, Maser E. J Steroid Biochem Mol Biol. 2012 Jan;128(1-2):51-5. Epub 2011 Oct 1. PMID: 22001161.

Microbial volatile organic compounds in moldy interiors: a long-term climate chamber study.
Schuchardt S, Strube A. J Basic Microbiol. 2012 Aug 23. doi: 10.1002/jobm.201200056. Journal of Basic Microbiology 2012, 52, 1-7. PMID: 22915248.

The use of biomarkers of toxicity for integrating in vitro hazard estimates into risk assessment for humans.
Blaauboer B J., Boekelheide K, Clewel H, Daneshian M, Dingemans M M L, Goldberg A M, Heneweer M, Jaworska J, Kramer N I, Leist M, Seibert H, Testai E, Vandebriel Rob J, Yager J D, Zurlo, J. ALTEX. 2012;29(4):411-25. doi: 10.14573/altex.2012.4.411.

Oligomerization and negative autoregulation of the LysR-type transcriptional regulator HsdR from Comamonas testosteroni.
Gong W, Xiong G, Maser E. Steroid Biochem Mol Biol. 2012 Jun 5;132(3-5):203-211. PMID: 22684002.

Expression of human carbonyl reductase 3 (CBR3; SDR21C2) is inducible by pro-inflammatory stimuli.
Malátková P, Ebert B, Wsól V, Maser E. Biochem Biophys Res Commun. 2012 Apr 6;420(2):368-73. Epub 2012 Mar 8. PMID: 22425771.

Steroids and microorganisms.
Maser E, Lanišnik Rižner T. J Steroid Biochem Mol Biol. 2012 Mar;129(1-2):1-3. doi: 10.1016/j.jsbmb.2012.01.002. Epub 2012 Jan 11. No abstract available. PMID: 22381541.

Genome sequence of Comamonas testosteroni ATCC 11996, a representative strain involved in steroid degradation.
Gong W, Kisiela M, Schilhabel MB, Xiong G, Maser E. J Bacteriol. 2012 Mar;194(6):1633-4. PMID: 22374961.

Targeting acetyl-CoA carboxylases: small molecular inhibitors and their therapeutic potential.
Luo DX, Tong DJ, Rajput S, Wang C, Liao DF, Cao D, Maser E. Recent Pat Anticancer Drug Discov. 2012 May 1;7(2):168-84. Review. PMID: 22339356.

Short-chain dehydrogenases/reductases in cyanobacteria.
Kramm A, Kisiela M, Schulz R, Maser E. FEBS J. 2012 Jan 17. doi: 10.1111/j.1742-4658.2012.08494.x. PMID: 22251568.

Identification and Characterization of the LysR-type Transcriptional Regulator HsdR for Steroid-inducible Expression of the 3α-Hydroxysteroid Dehydrogenase/Carbonyl Reductase Gene in Comamonas testosteroni.
Gong W, Xiong G, Maser E. Appl Environ Microbiol. 2012 Feb;78(4):941-50. doi: 10.1128/AEM.06872-11. PMID: 22156416.

Momordica charantia extract, a herbal remedy for type 2 diabetes, contains a specific 11β-hydroxysteroid dehydrogenase type 1 inhibitor.
Blum A, Loerz C, Martin HJ, Staab-Weijnitz CA, Maser E. J Steroid Biochem Mol Biol. 2012 Jan;128(1-2):51-5. Epub 2011 Oct 1. PMID: 22001161.

Specificity of Human Aldo-Keto Reductases, NAD(P)H:Quinone Oxidoreductase, and Carbonyl Reductases to Redox-Cycle Polycyclic Aromatic Hydrocarbon Diones and 4-Hydroxyequilenin-o-quinone.
Shultz CA, Quinn AM, Park JH, Harvey RG, Bolton JL, Maser E, Penning TM. Chem Res Toxicol. 2011 Dec 19;24(12):2153-66. Epub 2011 Sep 29. PMID: 21910479.

Hydroxysteroid dehydrogenases (HSDs) in bacteria - A bioinformatic perspective.
Kisiela M, Skarka A, Ebert B, Maser E. J Steroid Biochem Mol Biol. 2012 Mar;129(1-2):31-46. doi: 10.1016/j.jsbmb.2011.08.002. Epub 2011 Aug 22. PMID: 21884790.

 

2011

 

Cysteine proteases from Porphyromonas gingivalis and TLR ligands synergistically induce the synthesis of the cytokine IL-8 in human artery endothelial cells.
Deng S, Jepsen S, Dommisch H, Stiesch M, Fickenscher H, Maser E, Chen H, Eberhard J. Arch Oral Biol. 2011 Dec;56(12):1583-91. doi: 10.1016/j.archoralbio.2011.06.018. Epub 2011 Jul 30. PMID: 21802653.

Cytoprotective activity against peroxide-induced oxidative damage and cytotoxicity of flavonoids in C6 rat glioma cells.
Seibert H, Maser E, Schweda K, Seibert S, Gülden M. Food Chem Toxicol. 2011 Sep;49(9):2398-407. doi: 10.1016/j.fct.2011.06.055. Epub 2011 Jun 24. PMID: 21723910.

Proteasome inhibitors MG-132 and bortezomib induce AKR1C1, AKR1C3, AKR1B1, and AKR1B10 in human colon cancer cell lines SW-480 and HT-29.
Ebert B, Kisiela M, Wsól V, Maser E. Chem Biol Interact. 2011 May 30;191(1-3):239-49. doi: 10.1016/j.cbi.2010.12.026. Epub 2011 Jan 6.

Analysis of alternative promoter usage in expression of HSD11B1 including the development of a transcript-specific quantitative real-time PCR method.
Staab CA, Stegk JP, Haenisch S, Neiß E, Köbsch K, Ebert B, Cascorbi I, Maser E. Chem Biol Interact. 2011 May 30;191(1-3):104-12. doi: 10.1016/j.cbi.2010.12.027. Epub 2011 Jan 6.

Studies on reduction of S-nitrosoglutathione by human carbonyl reductases 1 and 3.
Staab, CA, Hartmanová T, El-Hawari Y, Ebert B, Kisiela M, Wsól V, Martin HJ, Maser E. Chem Biol Interact. 2011 May 30;191(1-3):95-103. doi: 10.1016/j.cbi.2011.01.016. Epub 2011 Jan 21.

Steroid degradation and two steroid-inducible enzymes in the marine bacterium H5.
Sang, Y, Xiong G, Maser E. Chem Biol Interact. 2011 May 30;191(1-3):89-94. doi: 10.1016/j.cbi.2011.01.027. Epub 2011 Jan 31.

Bioinformatic and biochemical characterization of DCXR and DHRS2/4 from Caenorhabditis elegans.
Kisiela M, El-Hawari Y, Martin HJ, Maser E. Chem Biol Interact. 2011 May 30;191(1-3):75-82. doi: 10.1016/j.cbi.2011.01.034. Epub 2011 Feb 15.

Identification of a new steroid degrading bacterial strain H5 from the Baltic Sea and isolation of two estradiol inducible genes.
Sang Y, Xiong G, Maser E. J Steroid Biochem Mol Biol. 2012 Mar;129(1-2):22-30. doi: 10.1016/j.jsbmb.2011.01.018. Epub 2011 Feb 15.

Manifold effects of palmitoylcarnitine on endoplasmic reticulum metabolism: 11β-hydroxysteroid dehydrogenase 1, flux through hexose-6-phosphate dehydrogenase and NADPH concentration.
Wang X, Mick GJ, Maser E, McCormick K. Biochem J. 2011 Jul 1;437(1):109-15. doi: 10.1042/BJ20102069.

THCVA-A - a new additional marker for illegal cannabis consumption.
Radünz L, Westphal G, Maser E. Rochholz G. Forensic Sci Int. 2012 Feb 10;215(1-3):171-4. doi: 10.1016/j.forsciint.2011.03.001. Epub 2011 Mar 31.

Enzymology and Molecular Biology of Carbonyl Metabolism, 15th International Meeting on Enzymology and Molecular Biology of Carbonyl Metabolism. Introduction.
Flynn TG, Kedishvili N, Maser E, O’Brien PJ, Plapp BV: Introduction Chem Biol Interact. 2011 May 30;191(1-3):1. doi: 10.1016/j.cbi.2011.03.002. Epub 2011 Mar 22.

 

2010

 

Peroxide-induced oxidative stress and cell death in C6 astroglioma cells.
Seibert H, Jess A, Linden A, Maser E, Perle M, Gülden M. ALTEX 27, Suppl. 2:123, 2010.

Concentration or dose: What is the proper measure for quantitative in vitro-in vivo extrapolation of toxic potency?
Gülden M, Seibert H. ALTEX 27, Suppl. 2:46, 2010.

Variability of elimination rate and cytotoxic potency of peroxides in C6 astroglioma cell cultures.
Kammann J, Gülden M, Maser E, Seibert H. ALTEX 27, Suppl. 2:65-66, 2010.

Effects of methylprednisolone and glatiramer acetate on nitric oxide formation of cytokine-stimulated cells from the rat oligodendroglial cell line OLN-93.
Holzknecht C, Röhl C. Neuroimmunomodulation. 2010;17(1):23-30. doi: 10.1159/000243082. Epub 2009 Oct 5.

11beta-Hydroxysteroid dehydrogenase type 1 is an important regulator at the interface of obesity and inflammation.
Staab C., Maser E. J Steroid Biochem Mol Biol. 2010 Mar;119(1-2):56-72. doi: 10.1016/j.jsbmb.2009.12.013. Epub 2010 Jan 5.

Lasting effect of preceding culture conditions on the susceptibility of C6 cells to peroxide-induced oxidative stress.
Brenner S, Gülden M, Maser E, Seibert H. Toxicol In Vitro. 2010 Dec;24(8):2090-6. doi: 10.1016/j.tiv.2010.06.005. Epub 2010 Jun 15.

The Comamonas testosteroni steroid biosensor system (COSS)-Reflection on other methods.
Maser E, Xiong G: J Steroid Biochem Mol Biol 2010 Aug;121(3-5):633-40. doi: 10.1016/j.jsbmb.2010.06.005. Epub 2010 Jun 15.

Regulation of human carbonyl reductase 3 (CBR3; SDR21C2) expression by Nrf2 in cultured cancer cells.
Ebert B, Kisiela M, Malátková P, El-Hawari Y, Maser E. Biochemistry, 2010 Oct 5;49(39):8499-511. doi: 10.1021/bi100814d. Epub 2010 Sep 8.

Cytotoxic potency of H2O2 in cell cultures: impact of cell concentration and exposure time.
Gülden M, Jess A, Kammann J, Maser E, Seibert H. Free Radic Biol Med. 2010 Nov 1;49(8):1298-305. doi: 10.1016/j.freeradbiomed.2010.07.015. Epub 2010 Jul 29.

Human carbonyl reductases.
Malátková P, Maser E, Wsól V. Curr Drug Metab, 11(8): 639-658, 2010

Mechanisms Involved in the Modulation of Astroglial Resistance to Oxidative Stress Induced by Activated Microglia: Antioxidative Systems, Peroxide Elimination, Radical Generation, Lipid Peroxidation.
Röhl C, Armbrust E, Herbst E, Jess A, Gülden M, Maser E, Rimbach G,
Bösch-Saadatmandi C. Neurotox Res. 2010 May;17(4):317-31. doi: 10.1007/s12640-009-9108-z. Epub 2009 Sep 10.

Characterization of the steroid degrading bacterium S19-1 from the Baltic Sea at Kiel; Germany.
Zhang T, Xiong G, Maser E. Chem Biol Interact. 2011 May 30;191(1-3):83-8. doi: 10.1016/j.cbi.2010.12.021. Epub 2010 Dec 24.

The Drosophila carbonyl reductase sniffer is an efficient 4-oxonon-2-enal (4ONE) reductase.
Martin HJ, Ziemba M, Kiesiela M, Botella JA, Schneuwly S, Maser E. Chem Biol Interact. 2011 May 30;191(1-3):48-54. doi: 10.1016/j.cbi.2010.12.006. Epub 2010 Dec 15.

Cloning, expression and characterization of a novel short-chain dehydrogenase/reductase (SDRx) in Comamonas testosteroni.
Gong W, Xiong G, Maser E. J Steroid Biochem Mol Biol. 2012 Mar;129(1-2):15-21. doi: 10.1016/j.jsbmb.2010.11.008. Epub 2010 Nov 24.

 

2009

 

Stoffmonographie Chlorphenole - Referenzwerte.
Kommission Humanbiomonitoring (Dr. Kruse als Mitglied). Bundesgesundheitsbl. Gesundheitsforsch Gesundheitsschutz 52 (10): 987 - 1001, 2009. DOI 10.1007/s00103-009-0947-9 Springer Medizin Verlag 2009.

Structural basis for substrate specificity in human monomeric carbonyl reductases.
Pilka ES, Niesen FH, Lee WH, El-Hawari Y, Dunford JE, Kochan G, Wsol V, Martin HJ, Maser E, Oppermann U. PLoS One. 2009 Oct 20;4(10):e7113. doi: 10.1371/journal.pone.0007113.

Cytotoxic, cytoprotective and antioxidant activities of resveratrol and analogues in C6 astroglioma cells in vitro.
Rüweler M, Gülden M, Maser E, Murias M, Seibert H. Chem Biol Interact. 2009 Dec 10;182(2-3):128-35. doi: 10.1016/j.cbi.2009.09.003. Epub 2009 Sep 8.

Approaching clinical proteomics: current state and future fields of application in cellular proteomics.
Apweiler R, Aslanidis C, Deufel T, Gerstner A, Hansen J, Hochstrasser D,
Kellner R, Kubicek M, Lottspeich F, Maser E, Mewes HW, Meyer HE, Müllner S, Mutter W, Neumaier M, Nollau P, Nothwang HG, Ponten F, Radbruch A, Reinert K, Rothe G, Stockinger H, Tárnok A, Taussig MJ, Thiel A, Thiery J, Ueffing M, Valet  G, Vandekerckhove J, Wagener C, Wagner O, Schmitz G. Cytometry A. 2009 Oct;75(10):816-32. doi: 10.1002/cyto.a.20779.

Partial purification and characterization of a new human membrane-bound carbonyl reductase playing a role in the deactivation of the anticancer drug oracin.
Skarydová L, Skarka A, Novotná R, Zivná L, Martin HJ, Wsól V, Maser E. Toxicology. 2009 Oct 1;264(1-2):52-60. doi: 10.1016/j.tox.2009.07.013. Epub 2009 Jul 25.

The organotin compounds trimethyltin (TMT) and triethyltin (TET) but not tributyltin (TBT) induce activation of microglia co-cultivated with astrocytes.
Röhl C., Grell M, Maser E. Toxicol In Vitro. 2009 Dec;23(8):1541-7. doi: 10.1016/j.tiv.2009.04.013. Epub 2009 May 5.

Effects of synthetic gestagens on fish reproduction.
Zeilinger J, Steger-Hartmann T, Maser E, Goller S, Vonk R, Länge R. Environ Toxicol Chem. 2009 Dec;28(12):2663-70. doi: 10.1897/08-485.1. Epub 2009 May 26.

Approaching clinical proteomics: current state and future fields of application in fluid proteomics.
Apweiler R, Aslanidis C, Deufel T, Gerstner A, Hansen J, Hochstrasser D,
Kellner R, Kubicek M, Lottspeich F, Maser E, Mewes HW, Meyer HE, Müllner S, Mutter W, Neumaier M, Nollau P, Nothwang HG, Ponten F, Radbruch A, Reinert K, Rothe G, Stockinger H, Tarnok A, Taussig MJ, Thiel A, Thiery J, Ueffing M, Valet  G, Vandekerckhove J, Verhuven W, Wagener C, Wagner O, Schmitz G. Clin Chem Lab Med.  2009;47(6):724-44. doi: 10.1515/CCLM.2009.167.

Proteomic identification of aldo-keto reductase AKR1B10 induction after treatment of colorectal cancer cells with the proteasome inhibitor bortezomib.
Loeffler-Ragg J, Mueller D, Gamerith G, Auer T, Skvortsov S. Sarg B, Skvortsova I, Schmitz KJ, Martin HJ, Krugmann J, Alakus H, Maser E, Menzel  J, Hilbe W, Lindner H, Schmid KW, Zwierzina H. Mol Cancer Ther. 2009 Jul;8(7):1995-2006. doi: 10.1158/1535-7163.MCT-08-0987. Epub 2009 Jun 30.

Analysis of the substrate-binding site of human carbonyl reductases CBR1 and CBR3 by site-directed mutagenesis.
El-Hawari Y, Favia AD, Pilka ES, Kisiela M, Oppermann U, Martin H-J. und Maser E. Chem Biol Interact. 2009 Mar 16;178(1-3):234-41. doi: 10.1016/j.cbi.2008.11.004. Epub 2008 Nov 18.

3alpha-Hydroxysteroid dehydrogenase/carbonyl reductase as a tool for isolation and characterization of a new marine steroid degrading bacterial strain.
Xiong G., Draus E, Luo Y und Maser E. Chem Biol Interact. 2009 Mar 16;178(1-3):206-10. doi: 10.1016/j.cbi.2008.10.033. Epub 2008 Nov 5.

Cis- and trans-regulatory elements of 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase as biosensor system for steroid determination in the environment.
Xiong G., Luo Y, Jin S, Maser E. Chem Biol Interact. 2009 Mar 16;178(1-3):215-20. doi: 10.1016/j.cbi.2008.10.012. Epub 2008 Oct 19.

11beta-Hydroxysteroid dehydrogenase type 1 inhibitors with oleanan and ursan scaffolds.
Blum A, Favia AD, Maser E. Mol Cell Endocrinol. 2009 Mar 25;301(1-2):132-6. doi: 10.1016/j.mce.2008.08.028. Epub 2008 Sep 6.

AKR1C3 as a potential target for the inhibitory effect of dietary flavonoids.
Skarydová L, Zivná L, Xiong G., Maser E., Wsól V. Chem Biol Interact. 2009 Mar 16;178(1-3):138-44. doi: 10.1016/j.cbi.2008.10.015. Epub 2008 Oct 19.

Role of human aldo-keto-reductase AKR1B10 in the protection against toxic aldehydes.
Martin H-J., Maser E. Chem Biol Interact. 2009 Mar 16;178(1-3):145-50. doi: 10.1016/j.cbi.2008.10.021. Epub 2008 Nov 1.

Expression profiles of human 11beta-hydroxysteroid dehydrogenases type 1 and type 2 in inflammatory bowel diseases.
Stegk J, Ebert B, Martin H-J, Maser E. Mol Cell Endocrinol. 2009 Mar 25;301(1-2):104-8. doi: 10.1016/j.mce.2008.10.030. Epub 2008 Oct 31.

The SDR (short-chain dehydrogenase/reductase and related enzymes) nomenclature initiative.
Persson B, Kallberg Y, Bray JE, Bruford E, Dellaporta SL, Favia AD, Duarte RG, Jörnvall H, Kavanagh KL, Kedishvili N, Kisiela M, Maser E., Mindnich R, Orchard S, Penning TM, Thornton JM, Adamski J und Oppermann U. Chem Biol Interact. 2009 Mar 16;178(1-3):94-8. doi: 10.1016/j.cbi.2008.10.040. Epub 2008 Nov 5.

Cancer biomarker AKR1B10 and carbonyl metabolism.
Balendiran GK, Martin H-J., El-Hawari Y, Maser E. Chem Biol Interact. 2009 Mar 16;178(1-3):134-7. doi: 10.1016/j.cbi.2008.10.044. Epub 2008 Nov 5.

Enzymology and molecular biology of carbonyl metabolism. Introduction.
Weiner H, Duester G, Maser E, Plapp B. Enzymology and Molecular Biology of Carbonyl Metabolism. Chem Biol Interact. 2009 Mar 16;178(1-3):1. doi: 10.1016/j.cbi.2008.11.003. Epub 2008 Nov 14.

Reductases.
Maser E. Encyclopedia of Cancer, Springer-Verlag, 2576-2581. doi: https://doi.org/10.1007/978-3-540-47648-1_5007.

Quantitative volatile metabolite profiling of common indoor fungi: relevancy for indoor air analysis.
Schuchardt S und Dr. Kruse. J Basic Microbiol. 2009 Aug;49(4):350-62. doi: 10.1002/jobm.200800152.